Lower Keys, FL Vacation Rentals

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USA > Florida > Lower Keys, FL

Make Lower Keys, FL your next getaway—choose from 283 great vacation rentals

Explore our Lower Keys vacation rentals

Explore Lower Keys, FL house rentals, condo rentals, studios, and more

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House rentals

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Condo rentals

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Studios

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Lower Keys, FL vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Tropical Sabbatical 3D Tour
1 Bed | 2 Bath | Sleeps 6

Tropical Sabbatical - Cudjoe Key, FL

From $149
Sunrise Suites - Paradise Escape 407 3D Tour
2 Bed | 2 Bath | Sleeps 6

Sunrise Suites - Paradise Escape 407 - Key West, FL

From $229
Casa Cubana @ Duval Square R14 3D Tour
2 Bed | 2.5 Bath | Sleeps 6

Casa Cubana @ Duval Square R14 - Key West, FL

From $370
Sunrise Suites - Sea Breeze Suite 101 3D Tour
2 Bed | 2 Bath | Sleeps 6

Sunrise Suites - Sea Breeze Suite 101 - Key West, FL

From $203
Old Town Garden Villas - Abaco Suite 3D Tour
1 Bed | 1.5 Bath | Sleeps 4

Old Town Garden Villas - Abaco Suite - Key West, FL

From $248

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Recent Lower Keys, FL vacation rental reviews

A big front porch...an ice-cold air conditioning unit...access to a pool but just far enough away to not notice other guests using it...easy walk to lots of great dining! The privacy of this fantastic cottage was unmatched. It was also spotlessly clean, and every single outlet and faucet and appliance worked as one would expect. This is the nicest rental home I have ever stayed in.
Natalie R. | Oct 2021
Resort community was awesome. Staff very friendly and helpful.
Michael G. | Oct 2021
We loved everything about this place except the beds. Very soft, and small! We had our boat at the dock, and it was great! Quick jaunt down the canal and you are in the bay. We fished and dove 7mile Bridge. We hung out at molasses key. We thoroughly enjoyed dinner at The Keys Steak and Lobster house. The pool was a must after 7 hours in the boat! Perfect for 3 or 4 people. Would have loved a fire pit at the end of a long day to relax by.
Rachel S. | Oct 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

When you’re looking for that perfect Florida Keys vacation rental, be sure to browse our Lower Keys beach houses and condos. Spanning the length of the legendary Overseas Highway, the Lower Keys area begins around Marathon and stretches to the southwest all the way to Key West. Whether you’re visiting for a weekend or the entire winter, a visit to a Lower Keys vacation rental guarantees tropical bliss.

Marathon and Key Colony Beach: the gateway to the Lower Keys


The town of Marathon, which technically encompasses several keys, is one of the most popular destinations in the Florida Keys. Key Colony Beach, the hub of Marathon, is home to several beautiful stretches of shoreline, as well as plenty of docks, restaurants, and luxurious vacation rentals to choose from. Like everywhere in the Lower Keys, the fishing and snorkeling surrounding Marathon are superb, so don’t be afraid to get out on the waves!

Cudjoe Key, the Torch Keys, and Sugarloaf Key


Cross the Seven Mile Bridge, and you’ll find the hidden gems of the Lower Keys: the Torch Keys, Cudjoe Key, and Sugarloaf Key. These less populous parts of the keys are home to some of our most secluded and beautiful Florida Keys vacation rentals, some of which are beachfront---an amenity in hot demand in the Lower Keys. Find your own little corner of paradise here, and you’re just a short car trip away from the hustle and bustle of Key West or Marathon.

Key West: the southern end of the Lower Keys


Colloquially recognized as the United States’ Southernmost Point, Key West is a historic and beautiful spot for a Keys getaway. Many of our Key West vacation rentals boast private pools, luxurious interiors, spacious patios, and rich history. Duval Street is the hub of most of the town’s action, with plenty of shopping, dining, and entertainment choices. Book a fishing excursion or sailing charter and enjoy the crystal-blue waters that surround you, or rent snorkeling gear and experience the area’s renowned coral reefs. A Key West vacation rental is the perfect place to spend the whole winter---snowbirds are welcome!

No matter where you're headed in the Lower Keys, we have a picturesque vacation home waiting for you. Book today!