Edisto Island Vacation Rentals

Compare 10 vacation rentals.
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Make Edisto Island your next getaway

Edisto Island

Explore Edisto Island house rentals, duplexes, condo rentals, and more

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House rentals

View 7 House rentals
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Duplexes

View 2 Duplexes
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Condo rentals

View 1 Condo rentals

Explore more vacation rental amenities in Edisto Island

Electric vehicle charger | Lake view | Lakefront | Ocean view | Riverfront | Sound view | Soundfront | Water view | Waterfront | A/C

Edisto Island vacation rentals for every getaway

Popular
Dog-friendly Internet Pool
Pineapple Villa
5 Bed | 4 Bath | Sleeps 12

Pineapple Villa - Edisto Island, SC

$533 avg / night
(excludes fees and taxes)
Oristo Haven
5 Bed | 4 Bath | Sleeps 11

Oristo Haven - Edisto Island, SC

$415 avg / night
(excludes fees and taxes)
Duke of Edisto
3 Bed | 2 Bath | Sleeps 6

Duke of Edisto - Edisto Island, SC

$263 avg / night
(excludes fees and taxes)
Edisto Hidden Oasis
4 Bed | 5 Bath | Sleeps 16

Edisto Hidden Oasis - Edisto Island, SC

$615 avg / night
(excludes fees and taxes)
4.67 (9)
In Spite of Ourselves
4 Bed | 3 Bath | Sleeps 13

In Spite of Ourselves - Edisto Island, SC

$688 avg / night
(excludes fees and taxes)
4.83 (30)

View 5 more homes

Recent Edisto Island vacation rental reviews

Wonderful home had a great Thanksgiving week with family. Plenty of room, lots of amenities and would book this again.
Pamela J. | Nov 2025
This is our second time renting here & we love it! It is perfect for our quick getaway to our favorite place!
Nathan B. | Nov 2025
Everything was very nice. Plenty of room. The boat ramp makes it nice for fishing. Will be back next year.
Michael H. | Nov 2025
Edisto Island Frequently Asked Questions

Yes. 212 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

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