South Carolina Vacation Rentals

Compare 2,276 vacation rentals. Enter your trip dates to get started.
USA > South Carolina

Make South Carolina your next getaway—choose from 2,276 great vacation rentals

Welcome to the Palmetto State, where opportunities for fun in the sun are unlimited. While this distinctly Southern state has seen rough times, it’s become a restful retreat for many vacationers. Its major cities, including Charleston and Columbia, still boast a laid-back vibe, welcoming visitors to slow down, stroll historic streets, and indulge in rich Southern food. South Carolina’s many vacation destinations draw guests from near and far who travel to stay in Hilton Head beach rentals, lakefront cabins, and everything in between.

Explore South Carolina condo rentals, house rentals, studios, and more

housing_type_condo.jpg

Condo rentals

View 1,090 Condo rentals
housing_type_house.jpg

House rentals

View 468 House rentals
housing_type_studio.jpg

Studios

View 431 Studios

South Carolina vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Carolinian Beach Resort 1001 3D Tour
0 Bed | 1 Bath | Sleeps 2

Carolinian Beach Resort 1001 - Myrtle Beach, SC

From $79
Carolinian Beach Resort 2031 3D Tour
1 Bed | 1 Bath | Sleeps 6

Carolinian Beach Resort 2031 - Myrtle Beach, SC

From $93
The Patricia Grand 1618 3D Tour
0 Bed | 1 Bath | Sleeps 2

The Patricia Grand 1618 - Myrtle Beach, SC

From $82
The Patricia Grand 0412 3D Tour
0 Bed | 1 Bath | Sleeps 4

The Patricia Grand 0412 - Myrtle Beach, SC

From $84
The Patricia Grand 1816 3D Tour
0 Bed | 1 Bath | Sleeps 2

The Patricia Grand 1816 - Myrtle Beach, SC

From $82

View 2,271 more homes

Recent South Carolina vacation rental reviews

Everything was great!
Kelly H. | Jul 2021
Loved the comfortable great room with lots of seating. Beds were wonderful and plenty of towels. Pool was a bonus.
Holly H. | Jul 2021
Lovely condo with beautiful view.
Janis S. | Jul 2021

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Beach destinations in South Carolina

If you’re looking for a beautiful South Carolina beach rental, look no further than Hilton Head Island. This wildly popular beach town is perfect for family vacations, romantic getaways, or golf retreats. Speaking of golf, Kiawah Island, farther up the coast, offers world-class golf in a beautiful resort setting.

Myrtle Beach boasts plenty of charms, too—if you’re looking to spend the winter in a South Carolina vacation rental, Myrtle Beach is the place to be. Snowbirds love spending the season at the sunny shores of Myrtle Beach, with its endless seafood, family-friendly entertainment, and relaxed atmosphere.

South Carolina lake vacations

If a lake trip is more your style, meander your way upstate to Lake Murray, one of South Carolina’s favorite lake destinations among locals and visitors alike. Columbia residents love Lake Murray as a quick getaway, at just a few miles outside the city limits. Water ski, explore the shoreline by bike, or try your luck dropping a fishing line—the options from your Lake Murray vacation rental are unlimited.

Our South Carolina vacation rentals provide a restful escape for you and your loved ones. Book today, and let the bliss begin.

Discover South Carolina

Pet-Friendly East Coast Vacations Your Dog Will Love

5 Oceanfront Hilton Head Vacation Rentals With Pools

Find the Perfect Myrtle Beach Condo Rental for You