Edisto Island Vacation Rentals

Compare 119 vacation rentals.
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Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, townhouses, and more

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House rentals

View 87 House rentals
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Condo rentals

View 17 Condo rentals
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Townhouses

View 11 Townhouses

Explore more vacation rental amenities in Edisto Island

Pool | Electric vehicle charger | Lake view | Lakefront | Ocean view | Oceanfront | Riverfront | Water view | Waterfront | A/C

Edisto Island vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Weeks End
4 Bed | 2 Bath | Sleeps 12

Weeks End - Edisto Beach, SC

$473 avg / night
(excludes fees and taxes)
Driftwood Villa 262
1 Bed | 1 Bath | Sleeps 4

Driftwood Villa 262 - Edisto Beach, SC

$215 avg / night
(excludes fees and taxes)
4.2 (5)
Driftwood Villa 280
1 Bed | 1 Bath | Sleeps 4

Driftwood Villa 280 - Edisto Beach, SC

$209 avg / night
(excludes fees and taxes)
3.8 (5)
The Pirate Den
3 Bed | 3 Bath | Sleeps 10

The Pirate Den - Edisto Beach, SC

$344 avg / night
(excludes fees and taxes)
4.2 (5)
Ebb and Flow
2 Bed | 2 Bath | Sleeps 10

Ebb and Flow - Edisto Beach, SC

$269 avg / night
(excludes fees and taxes)
4.4 (5)

View 114 more homes

Recent Edisto Island vacation rental reviews

Location and view
Anna M. | Mar 2026
Close access to beach. House was the perfect size for family and friends
Mary M. | Mar 2026
We love this house and have rented it many times. It is clean and comfortable and we will rent again. Best location.
Marsha S. | Mar 2026
Edisto Island Frequently Asked Questions

Yes, 44 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 118 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning


Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.

People also search for

Edisto Beach   |   Edisto Island   |   South Carolina
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