Edisto Island Vacation Rentals

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USA > South Carolina > Edisto Island

Make Edisto Island your next getaway—choose from 106 great vacation rentals

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, townhouses, cottages, and more


House rentals

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Edisto Island vacation rentals for every getaway

Dog-friendly Hot tub Internet
Heh Edisto 3D Tour
3 Bed | 2 Bath | Sleeps 6

Heh Edisto - Edisto Beach, SC

From $279
Sto-Away 3D Tour
4 Bed | 4 Bath | Sleeps 14

Sto-Away - Edisto Beach, SC

From $449
Sea-Esta 3D Tour
1 Bed | 1 Bath | Sleeps 2

Sea-Esta - Edisto Beach, SC

From $127
The Blue Pelican 3D Tour
5 Bed | 3 Bath | Sleeps 13

The Blue Pelican - Edisto Beach, SC

From $449
Driftwood Villa - 262 3D Tour
1 Bed | 1 Bath | Sleeps 4

Driftwood Villa - 262 - Edisto Beach, SC

From $132

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Recent Edisto Island vacation rental reviews

Unbelievably clean! Very easy walk to an uncrowded beach. Well-equipped and spacious kitchen. Easy drive to a variety of restaurants. Will definitely be back!
Mary F. | May 2022
Bay Creek 212 was a great villa for our needs. The beds were super comfortable and the blackout curtains were ideal for when we didn't want to wake up with the sun. Just a word to the wise, if you're cooking in the oven, make sure the sliding and main doors are open with the screens closed allowing for better ventilation...and no I didn't burn the bacon. :) Otherwise, great location with perfect access to the elevator for those with ambulatory issues and great atmosphere. We will definitely keep Bay Creek 212 on our rotation of locations.
Kristin C. | May 2022
Large open area. Good counter space, beds were comfortable, amenities were ample. I will definatly rent again.
Lorraine S. | May 2022

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.