South Carolina Vacation Rentals

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Make South Carolina your next getaway

From the sun-kissed shores of Myrtle Beach to the historic charm of Charleston, South Carolina offers something for every kind of traveler. Whether you're teeing off on world-class golf courses, savoring Lowcountry cuisine, or exploring lush maritime forests, Vacasa has the perfect vacation rental for your stay.

Explore South Carolina condo rentals, house rentals, villas, and more

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Condo rentals

View 1,672 Condo rentals
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House rentals

View 515 House rentals
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Villas

View 77 Villas

South Carolina vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Landmark Resort 920
0 Bed | 1 Bath | Sleeps 4

Landmark Resort 920 - Myrtle Beach, SC

$91 avg / night
(excludes fees and taxes)
2.67 (3)
The Patricia Grand 0724
0 Bed | 1 Bath | Sleeps 2

The Patricia Grand 0724 - Myrtle Beach, SC

$154 avg / night
(excludes fees and taxes)
3.45 (40)
Modern Beachfront Bliss: 2BR/2BA Luxury Villa
2 Bed | 2 Bath | Sleeps 6

Modern Beachfront Bliss: 2BR/2BA Luxury Villa - Hilton Head, SC

$206 avg / night
(excludes fees and taxes)
Palace Resort 706
0 Bed | 1 Bath | Sleeps 4

Palace Resort 706 - Myrtle Beach, SC

$119 avg / night
(excludes fees and taxes)
5.0 (1)
Steps to Sand: Ocean Villa with Pool & Tennis
1 Bed | 1 Bath | Sleeps 6

Steps to Sand: Ocean Villa with Pool & Tennis - Hilton Head, SC

$146 avg / night
(excludes fees and taxes)

View 2,451 more homes

Recent South Carolina vacation rental reviews

Very clean and friendly
Janet & Dennis C. | Mar 2026
Very spacious and good staff
Keonica I. | Mar 2026
The condo is beautifully decorated and the location perfect in Coligny. Only downside was WIFI availability is through Vacasa and for work purposes didn't meet my needs. Immaculate throughout and the amenities were all available. Would like to rent there again.
Sandi G. | Mar 2026
South Carolina Frequently Asked Questions

Yes, 323 of our South Carolina homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 2375 of our South Carolina vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our South Carolina vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local South Carolina team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for South Carolina, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Stay where Southern hospitality meets coastal charm

Our South Carolina vacation rentals range from oceanfront condos with resort-style pools to secluded beach homes on Kiawah and Hilton Head Island. Enjoy amenities like private balconies, full kitchens, and direct beach access—all just minutes from the state's most beloved attractions.

Your South Carolina adventure starts now

Relax on the sandy shores of Folly Beach, take a scenic boat tour through the salt marshes, or immerse yourself in Charleston’s rich history and vibrant culinary scene. However you vacation, make it unforgettable with a Vacasa rental in South Carolina. Browse our homes and start planning your perfect getaway today.

Do you offer snowbird or long-term rentals in South Carolina? 

Yes, we have an excellent selection of snowbird rental properties available throughout South Carolina's coastal regions and inland destinations. Whether you prefer a cozy beach house on Hilton Head Island or a spacious villa in Myrtle Beach, our South Carolina snowbird rentals offer a welcoming escape from the cold.

Explore snowbird and long-term rentals in South Carolina >

South Carolina travel inspiration

Explore South Carolina snowbird rentals

Explore snowbird rentals in Myrtle Beach, SC

Explore long-term rentals in Hilton Head, SC

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Travel Guide: Things to do in Charleston, SC

Travel Guide: Things to do in Myrtle Beach, SC

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