Cayo District Vacation Rentals

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Belize > Cayo District

Make Cayo District your next getaway—choose from 26 great vacation rentals

The Cayo District in Belize is home to a rich diversity of people and wildlife. This area boasts some of the country's biggest cities, as well as handfuls of small villages and natural forest reserves. It is the second largest district in Belize, with over 2,000 square miles of beautiful landscape housing around 60,000 people. Get a taste of culture in the cities, then head out to explore jungles, rivers, waterfalls, caves, and Mayan ruins.

Extending west from the nation's capital, Belmopan, lush valleys turn into rolling hills that consist largely of farmland. Cayo is known for its agriculture, providing succulent tropical fruits as well as most of the nation's livestock, poultry, and grain. While English and Spanish are the nation's primary languages, there is a large population of Latinos, Creoles, Chinese, Lebanese, Guatemlans, Mennonites, and Mayas, so you're sure to have a diverse experience during your stay in one of our Cayo vacation rentals!

Near the border of Guatemala, the twin cities of San Ignacio and Santa Elena are the country's second largest population center. Here you can experience a bustling market that draws thousands on weekends and a vibrant nightlife that goes until morning. Hike or horseback ride up to the iconic Maya site, Cahal Pech, atop a hill just a mile outside of town to see amazing ruins and a breathtaking panoramic view of the city and the Belize River Valley. 

Whether you prefer cities or wilderness, there's a unique experience for everyone waiting in the Cayo District of Belize!

Explore Cayo District house rentals, hotel suites, apartments, and more

House rentals

View 11 House rentals

Hotel Suites

View 4 Hotel Suites


View 3 Apartments

Cayo District vacation rentals for every getaway

Dog-friendly Internet Pool
Palace at D Borland View *Gold Standard Certified
5 Bed | 3 Bath | Sleeps 8

Palace at D Borland View *Gold Standard Certified - San Ignacio, Ca

$496 avg / night
La Casita @ Midas Belize
2 Bed | 1 Bath | Sleeps 6

La Casita @ Midas Belize - San Ignacio, Ca

$196 avg / night
Jaguar  Room @ Mahogany Hall *Gold Standard Certified
0 Bed | 1 Bath | Sleeps 2

Jaguar Room @ Mahogany Hall *Gold Standard Certified - San Ignacio, Ca

$115 avg / night
Monkey Suite @ Mahogany Hall *Gold Standard Certified
1 Bed | 1 Bath | Sleeps 4

Monkey Suite @ Mahogany Hall *Gold Standard Certified - San Ignacio, Ca

$158 avg / night
Divina @ Framadani Estate
2 Bed | 2.5 Bath | Sleeps 4

Divina @ Framadani Estate - San Ignacio, Ca

$371 avg / night

View 21 more homes

Recent Cayo District vacation rental reviews

The hotel is beautiful, the food is great and the staff are incredibly helpful and friendly
Lisa S. | Nov 2022
This beautiful, stately home on the river is a relaxing oasis. Tourists can explore the Myon ruins nearby and the caves for adventure, and then relax by the water in the pool with delicious meals at this gorgeous little inn. The staff is so kind!
Thompson K. | Nov 2022
The Resort offers a quiet & pleasant environment the staff is very careful
christele l. | Oct 2022
Cayo District Frequently Asked Questions

Yes. 26 of our Cayo District vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >

Some of the most popular amenities in our Cayo District vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Cayo District team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Cayo District, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning