Mission Bay Beach House Rentals

Compare 271 vacation rentals. Enter your trip dates to get started.
USA > California > Mission Bay

Make Mission Bay your next getaway—choose from 271 great vacation rentals

For a fun-filled vacation on the water, look no further than our beautiful and diverse selection of Mission Bay beach house rentals! Located in sunny Southern California, Mission Bay is one of the area's top destinations for a wide variety of water sports.

Explore Mission Bay house rentals, condo rentals, duplexes, and more

House rentals

View 112 House rentals
housing_type_condo.jpg

Condo rentals

View 78 Condo rentals

Duplexes

View 49 Duplexes

Mission Bay vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Mission Beach - Ocean and Bay Steps Away!
2 Bed | 2 Bath | Sleeps 6 (4 Adults Max)

Mission Beach - Ocean and Bay Steps Away! - San Diego, CA

$398 avg / night
Ventura Place by the Sea #6
0 Bed | 1 Bath | Sleeps 4

Ventura Place by the Sea #6 - San Diego, CA

$284 avg / night
Mission Manor
2 Bed | 2 Bath | Sleeps 6

Mission Manor - San Diego, CA

$439 avg / night
Cottage By Mission Bay
0 Bed | 1 Bath | Sleeps 2

Cottage By Mission Bay - San Diego, CA

$213 avg / night
Ocean Way - Unit B
1 Bed | 1 Bath | Sleeps 4

Ocean Way - Unit B - San Diego, CA

$379 avg / night

View 266 more homes

Recent Mission Bay vacation rental reviews

House was clean, spacious, well equipped, and in a wonderful central location. We had three families there for a few days through Thanksgiving and all really enjoyed our time together and the house!
Bill B. | Nov 2022
Clean and well stocked rental. Will be back again. They had plenty of little things that come in handy like a flashlights. Extra beach towels and beach chairs etc. Quiet neighborhood as well with no cars. Easy walk to the bay and short 1 walk to the beach boardwalk.
Joshua M. | Nov 2022
love the location, love the three level design
ANDY L. | Nov 2022
Mission Bay Frequently Asked Questions

Yes, 90 of our Mission Bay homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 269 of our Mission Bay vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Mission Bay vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Mission Bay team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Mission Bay, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning


Our Mission Bay vacation rentals are a popular choice for visitors year-round and offer plenty of options for recreation and relaxation.

Things to do in Mission Bay

While the saltwater bay is the area's main attraction, you'll find plenty of ways—both on the water and on land—to spend your days when you stay in one of our homes in this waterfront neighborhood on the outskirts of San Diego. The hardest part of your stay is going to be trying to figure out what to do first!

Golf enthusiasts can practice their swing at the Mission Bay Golf Course. Originally built in 1955, the now 18-hole executive course is the only one in the San Diego area that offers night lighting. The area's other attractions include the Mission Bay Aquatic Center and the dog-friendly Fiesta Island. Of course, if you are looking for a big city experience, you can spend your day exploring the sights and sounds of downtown San Diego.

Mission Bay Park

With 27 miles of shoreline and sandy beaches galore, Mission Bay Park draws swimmers, kayakers and paddlers, sailors, boaters, jet skiers, fishermen, golfers, birders, picnickers, beach volleyball enthusiasts, bicyclists - you name it, you can do it all at Mission Bay.

The saltwater bay is part of Mission Bay Park, the largest aquatic park in the world, so you'll spend your days enjoying the area's natural beauty. Even SeaWorld San Diego, one of Southern California's most popular tourism destinations, is located within the park. Also in the neighborhood is the historic seaside amusement park Belmont Park. With wooden rollercoasters and a variety of thrilling rides, this popular attraction promises plenty of fun for the entire family.

Mission Bay and the surrounding area

Mission Bay is side-by-side with the funky Mission Beach neighborhood, with miles of sandy Pacific shoreline, two popular boardwalks, and excellent surfing, dining and shopping. Book one of our Mission Bay vacation rentals and you'll be within reach of all the services you might need for an easy beach vacation, yet with close proximity to downtown San Diego and other popular San Diego neighborhoods and beaches, making it a great home base from which to explore the city at large. Downtown San Diego, the nightlife of Pacific Beach, and laid-back La Jolla Village are all less than 10 miles from the Bay.

With fun and relaxation to be had from sun up to sun down, our selection of centrally-located Mission Bay cottages and condo rentals are the perfect choice for your next beach getaway!