Port St. Lucie Vacation Rentals

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Make Port St. Lucie your next getaway

Port St. Lucie makes sense when you plan it as an inland Treasure Coast base rather than a beachfront town. Keep the core stay focused on PGA Golf Club, Clover Park, Savannas Preserve State Park, and the Botanical Gardens, then save Fort Pierce, Hobe Sound, or Jupiter for dedicated coastal outings.

Explore Port St. Lucie house rentals, apartments, and more

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House rentals

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Apartments

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Port St. Lucie vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Private Pool & Yard: Family Home in Port St Lucie
3 Bed | 2 Bath | Sleeps 8

Private Pool & Yard: Family Home in Port St Lucie - Port St. Lucie, FL

$459 avg / night
(excludes fees and taxes)
Stuart Apartment w/ Patio Near St Lucie River!
1 Bed | 1 Bath | Sleeps 2

Stuart Apartment w/ Patio Near St Lucie River! - Port St. Lucie, FL

$183 avg / night
(excludes fees and taxes)
5.0 (9)
Port St Lucie Vacation Home w/ Lanai & Pool!
2 Bed | 1.5 Bath | Sleeps 4

Port St Lucie Vacation Home w/ Lanai & Pool! - Port St. Lucie, FL

$224 avg / night
(excludes fees and taxes)
5.0 (3)
Beach-Hop & Golf! Port St Lucie Apt w/ Shared Yard
1 Bed | 1 Bath | Sleeps 2

Beach-Hop & Golf! Port St Lucie Apt w/ Shared Yard - Port St. Lucie, FL

$195 avg / night
(excludes fees and taxes)
10 Mi to Public Beaches: Port St Lucie Getaway
3 Bed | 2 Bath | Sleeps 4

10 Mi to Public Beaches: Port St Lucie Getaway - Port St. Lucie, FL

$326 avg / night
(excludes fees and taxes)
3.0 (1)

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Recent Port St. Lucie vacation rental reviews

Nice house. Very welcoming.
Leigha . | Apr 2026
We loved it! My family and I had a fabulous time. It was clean had basics the only thing it needs coolers and beach essentials 😁 we paid extra to get pool heated and that made the pool more enjoyable in evenings . Had plenty of entertainment options my boys loved the ping pong table kept them off electronics so I call it a win. We also enjoyed how private the backyard is and it's so close to a lot of shopping and restaurants.
Abigail . | Jan 2026
The house had everything we needed, and some things we didn't know we needed! It is beautifully decorated, and has many spaces to spread out from the amazing patio, large open kitchen, and huge sectional couch. Communication with the host was excellent, and all of our family members agreed it was the best rental we every had. Highly recommend!
Cindy . | Jan 2026
Port St. Lucie Frequently Asked Questions

Yes, 8 of our Port St. Lucie homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 131 of our Port St. Lucie vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Port St. Lucie vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Port St. Lucie team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Port St. Lucie, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Plan your Port St. Lucie getaway

Port St. Lucie vacation rentals work well for travelers who want a relaxed Treasure Coast base with golf, baseball, preserves, gardens, and nearby Atlantic coast day trips. Families, couples, golf groups, and sports fans can plan around PGA Golf Club, Clover Park, Savannas Preserve State Park, and Port St. Lucie Botanical Gardens before heading out to Fort Pierce or Hobe Sound.

As you compare homes, think about whether you want to stay near golf, close to Tradition dining, near preserve access, or in a quieter residential setting with room to unwind. Each home is unique, so review listing details for parking, kitchens, pet policies, WiFi, laundry, pools, outdoor space, and seasonal access notes before you book.

Things to do in Port St. Lucie

Looking for things to do in Port St. Lucie, FL? Start with the city’s golf, baseball, gardens, and preserves, then keep Treasure Coast beaches, wildlife refuges, and lighthouse outings in a separate day-trip plan.

Savannas Preserve State Park

Savannas Preserve State Park gives Port St. Lucie visitors a protected coastal-scrub landscape with trails, wetlands, and wildlife habitat. It’s the in-town nature anchor for travelers who want an easy outdoor plan without leaving the area.

Best for:

PGA Golf Club

PGA Golf Club is a major Port St. Lucie golf destination tied to the PGA brand, with multiple courses that make the city especially appealing to golf-focused travelers. It’s a strong anchor for golf trips, multigenerational groups, and visitors who want a recognizable activity close to their rental.

Best for:

Clover Park

Clover Park is Port St. Lucie’s baseball venue and the spring training home of the New York Mets. It’s the city’s marquee sports and event draw, especially for families and fans building a getaway around baseball.

Best for:

Port St. Lucie Botanical Gardens

Port St. Lucie Botanical Gardens is a community garden destination with themed garden areas and a calm, low-key pace. It works well for couples, families, and plant lovers looking for a softer activity between golf, baseball, or beach-day plans.

Oxbow Eco-Center

Oxbow Eco-Center is a St. Lucie County environmental learning center with trails and exhibits that make local ecology approachable. It’s a good low-pressure nature stop for families and curious travelers who want more context on the region’s habitats.

Where to eat in Port St. Lucie

Port St. Lucie dining is strongest when planned around established clusters rather than a long list of individual restaurants. Tradition is the easiest area to start, with a town-center-style layout and a concentration of restaurants, cafes, and casual dining options that work well for a walkable meal plan.

If you prefer relaxed meals at your rental, check each listing for kitchen setup, dining space, outdoor seating, grill details, and parking. Features vary by home, so confirm the setup that matters most before booking.

Port St. Lucie local tips

Day trips from Port St. Lucie

Port St. Lucie makes a practical Treasure Coast base for beach days, military history, coastal refuges, and lighthouse outings. Plan these as separate half-day or full-day trips, and check current hours, tickets, road conditions, and beach or refuge access before you go.

Fort Pierce Inlet State Park

Fort Pierce Inlet State Park is a barrier-island state park in nearby Fort Pierce with Atlantic beach scenery, inlet views, and a distinctly coastal feel. It’s a strong beach-day option for travelers who want ocean access while staying in Port St. Lucie.

National Navy UDT-SEAL Museum

National Navy UDT-SEAL Museum in Fort Pierce is dedicated to the history of Navy frogmen and SEAL teams. It works well for history-minded travelers or families pairing Fort Pierce beach time with an indoor museum stop.

Nathaniel P. Reed Hobe Sound National Wildlife Refuge

Nathaniel P. Reed Hobe Sound National Wildlife Refuge protects coastal habitat, wildlife, and conservation landscapes on the southern Treasure Coast. It’s a quieter nature-focused day trip for travelers who want a less commercial coastal experience.

Jupiter Inlet Lighthouse and Museum

Jupiter Inlet Lighthouse and Museum gives visitors a historic coastal outing centered on one of the region’s most recognizable waterfront icons. Plan it as a regional heritage stop that pairs well with a broader Jupiter or inlet-area day trip.