Edisto Island Vacation Rentals

Compare 118 vacation rentals.
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Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, duplexes, and more

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House rentals

View 85 House rentals
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Condo rentals

View 17 Condo rentals
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Duplexes

View 9 Duplexes

Explore more vacation rental amenities in Edisto Island

Pool | Electric vehicle charger | Lake view | Lakefront | Ocean view | Oceanfront | Riverfront | Sound view | Soundfront | Water view

Edisto Island vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Heh Edisto
3 Bed | 2 Bath | Sleeps 6

Heh Edisto - Edisto Beach, SC

$258 avg / night
(excludes fees and taxes)
4.56 (50)
Oristo Haven
5 Bed | 4 Bath | Sleeps 11

Oristo Haven - Edisto Island, SC

$443 avg / night
(excludes fees and taxes)
5.0 (1)
Bay Creek Villa 304 - Just Coastin'
2 Bed | 2 Bath | Sleeps 4

Bay Creek Villa 304 - Just Coastin' - Edisto Beach, SC

$253 avg / night
(excludes fees and taxes)
4.87 (39)
Life of Rylee
6 Bed | 3 Bath | Sleeps 14

Life of Rylee - Edisto Beach, SC

$935 avg / night
(excludes fees and taxes)
4.62 (65)
All Decked Out
3 Bed | 2 Bath | Sleeps 8

All Decked Out - Edisto Beach, SC

$356 avg / night
(excludes fees and taxes)
4.63 (54)

View 113 more homes

Recent Edisto Island vacation rental reviews

This condo was exceptionally outfitted and decorated with nice little things all over. The views and location were great. We liked the first floor location. The bedroom is so small we had to put our suitcases on the dining table but we didn't eat there anyway. A really nice place.
Bruce S. | Feb 2026
Close to beach and Whaleys. Walking distance. Clean home with lots of space and parking.
Glynna F. | Jan 2026
The Location. The cleanliness. The space.
Ken H. | Jan 2026
Edisto Island Frequently Asked Questions

Yes, 44 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 118 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning


Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.

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Edisto Island   |   Edisto Beach   |   South Carolina
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