Missouri Vacation Rentals

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Make Missouri your next getaway

Missouri is a state where rivers write the story, music fills the towns, and outdoor adventures are balanced by friendly hospitality. From the Ozark Mountains to the banks of the Mississippi River, Missouri offers a versatile mix of scenic landscapes, thriving cities, and historic small towns. Whether you’re paddling clear streams, exploring rock formations, or enjoying live music and great food, Missouri is a destination full of discovery.

Explore Missouri house rentals, apartments, condo rentals, and more

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House rentals

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Apartments

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Condo rentals

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Missouri vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Eternal Sunrises
2 Bed | 2 Bath | Sleeps 7

Eternal Sunrises - Sunrise Beach, MO

$130 avg / night
(excludes fees and taxes)
Rustic 2BR Cabin - Wooded View - Seasonal Pool
2 Bed | 2 Bath | Sleeps 4

Rustic 2BR Cabin - Wooded View - Seasonal Pool - Reeds Spring, MO

$181 avg / night
(excludes fees and taxes)
Lakeside Hideaway
3 Bed | 3 Bath | Sleeps 14

Lakeside Hideaway - Osage Beach, MO

$346 avg / night
(excludes fees and taxes)
Charming 3BR Cabin - LAKE VIEW - Camdenton
3 Bed | 2 Bath | Sleeps 8

Charming 3BR Cabin - LAKE VIEW - Camdenton - Camdenton, MO

$239 avg / night
(excludes fees and taxes)
Vineyards 2909 #3
3 Bed | 2 Bath | Sleeps 8

Vineyards 2909 #3 - Branson, MO

$181 avg / night
(excludes fees and taxes)
4.28 (40)

View 544 more homes

Recent Missouri vacation rental reviews

It was spacious and comfortable with everything we needed for a great one week vacation.
Joel F. | Jun 2026
It was easy to get to! Great layout! Everything you needed for a couple nights stay!
Blake M. | Jun 2026
The little house was clean. The shower was very good. The loft is difficult to get in and out of bed probably no way around that the way the house is built. The little couch on the first floor is comfortable. My suggestion would be to make it a pull out. The second loft looks very dangerous.
Becky . | May 2026
Missouri Frequently Asked Questions

Yes, 147 of our Missouri homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 540 of our Missouri vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Missouri vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Missouri team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Missouri, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Why visit Missouri?

Missouri is where Southern warmth meets Midwestern resilience. It's great for family vacations, road trips, outdoor escapes, or quick weekends in cities like St. Louis or Kansas City. You’ll find winding rivers, state parks, lakefront towns, Civil War history, and some of the best BBQ in the country. And with four distinct seasons, Missouri's scenery shifts beautifully year-round, from dogwoods blooming in spring to golden Ozark trails in fall.

Whether you’re floating downriver, tapping your foot to blues, or touring vineyards near the Missouri wine country, it’s easy to find your pace here. 

Things to do in Missouri

Where to stay in Missouri

Vacation rentals in Missouri include everything from rustic cabins and riverfront lodges in the Ozarks to downtown lofts in Kansas City and St. Louis. Lakefront homes in places like Lake of the Ozarks are perfect for summer escapes, while cozy cottages and vineyard-adjacent properties make ideal weekend retreats. Rentals are popular for their space, comfort, and easy access to both nature and cultural attractions.

Whether you're coming for outdoor adventure or a food-filled city trip, Missouri's vacation homes are designed to fit every style and season of travel. 

A crossroads of comfort, nature, and culture

Missouri invites you to take your time, explore your interests, and feel more connected with nature, history, and the people you meet. From river towns to rugged bluffs and from jazz clubs to forest cabins, it’s a place that combines variety with heartfelt simplicity. Come for a weekend or stay longer, you’ll find the stories here are still being written.