Missouri is a state where rivers write the story, music fills the towns, and outdoor adventures are balanced by friendly hospitality. From the Ozark Mountains to the banks of the Mississippi River, Missouri offers a versatile mix of scenic landscapes, thriving cities, and historic small towns. Whether you’re paddling clear streams, exploring rock formations, or enjoying live music and great food, Missouri is a destination full of discovery.
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Yes, 41 of our Missouri homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).
Browse dog-friendly homes >Yes. 127 of our Missouri vacation rentals have internet access, so you can stay connected throughout your trip.
Browse homes with internet access >Absolutely. Our local Missouri team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.
Learn more about Vacasa Premium Clean >Missouri is where Southern warmth meets Midwestern resilience. It's great for family vacations, road trips, outdoor escapes, or quick weekends in cities like St. Louis or Kansas City. You’ll find winding rivers, state parks, lakefront towns, Civil War history, and some of the best BBQ in the country. And with four distinct seasons, Missouri's scenery shifts beautifully year-round, from dogwoods blooming in spring to golden Ozark trails in fall.
Whether you’re floating downriver, tapping your foot to blues, or touring vineyards near the Missouri wine country, it’s easy to find your pace here.
Explore the Ozarks: Hike, bike, or paddle through forested trails, scenic byways, and clear freshwater streams in southern Missouri.
Catch a show in Branson: This family-friendly entertainment hub offers theaters, live music, and amusement parks nestled in the hills.
Visit Gateway Arch National Park in St. Louis: Ride to the top of the nation's tallest monument and explore riverside museums and parks.
Walk the streets of Kansas City's Crossroads District: Sample local barbecue, watch jazz shows, and visit small galleries and murals.
Paddle or tube the Current and Jacks Fork Rivers: These protected spring-fed rivers offer some of the clearest and most scenic floats in the Midwest.
Tour charming small towns like Hermann or Rocheport: Enjoy wine tasting, river views, and restored downtowns with a relaxed, historic feel.
Vacation rentals in Missouri include everything from rustic cabins and riverfront lodges in the Ozarks to downtown lofts in Kansas City and St. Louis. Lakefront homes in places like Lake of the Ozarks are perfect for summer escapes, while cozy cottages and vineyard-adjacent properties make ideal weekend retreats. Rentals are popular for their space, comfort, and easy access to both nature and cultural attractions.
Whether you're coming for outdoor adventure or a food-filled city trip, Missouri's vacation homes are designed to fit every style and season of travel.
Missouri invites you to take your time, explore your interests, and feel more connected with nature, history, and the people you meet. From river towns to rugged bluffs and from jazz clubs to forest cabins, it’s a place that combines variety with heartfelt simplicity. Come for a weekend or stay longer, you’ll find the stories here are still being written.